Preclinical Biological Evaluation of Medical Devices Interacting with Blood

One of the most important safety tests for blood-contacting medical devices is hemocompatibility. Hemocompatibility ensures that a device does not cause red blood cell destruction through hemolysis, cause clotting that could lead to the formation of a thrombus, activate platelets, activate the complement system, or bind platelets, and leukocytes.

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